Don’t Take Aspirin and Warfarin Together
There are a number of risks associated with Aspirin and Warfarin. In addition to bleeding complications, they may increase the risk of necrosis, or death from a bleed. Stopping the two medications may decrease bleeding risks without apparent harm. However, you must consult your doctor for advice. The two antiplatelet drugs can interact dangerously, and should never be taken together.
Aspirin
Warfarin and aspirin should never be taken together. This is the advice of the University of Michigan. Taking them together increases bleeding risk. The researchers looked at over 6,000 patients who were taking warfarin for conditions like A-fib and blood clots. They were also asked if they were taking aspirin. Those who were taking aspirin had a reduced risk of bleeding events. Those who were not taking aspirin were not at an increased risk of blood clots.
Warfarin tablets are usually prescribed to people with APS and a history of blood clots. Women who are pregnant or trying to conceive should consult a doctor before taking warfarin. In more severe cases, warfarin is given as injections. These can be given at home or in hospital. While side effects are generally mild, the interruption of blood clotting can lead to excessive bleeding.
Antiplatelet drugs
Antiplatelet drugs are used to treat and prevent heart attacks and strokes. They must be taken at low dosages, and patients should be monitored closely for bleeding risks. The antiplatelet drugs are metabolized in the liver, and patients with poor liver function may not be able to metabolize them properly. In these cases, it is important to use a lower dose of aspirin.
Patients taking antiplatelet drugs should also discuss potential risks with their health care providers. These medicines may interact with pregnancy, breastfeeding, and other conditions. Changing or stopping your medication without a healthcare provider’s approval may result in serious side effects.
Necrosis
One report highlights the potential risk of Necrosis when taking Aspirin or Warfarin together. The disease has been associated with a variety of causes, including calciphylaxis, end-stage renal disease, and hyperparathyroidism. However, in other patients, the condition may occur without any obvious cause.
Taking warfarin is a common treatment for deep vein thrombosis, as well as for preventing further emboli in patients with pulmonary embolism. It is also used to reduce the risk of stroke or heart attack in patients with atrial fibrillation. It is also used to prevent blood clots after surgery, such as a coronary stent.
Bleeding
One of the risks of taking Aspirin and Warfarin together is bleeding. The two drugs are often prescribed together, but only in very limited circumstances. In patients with recent acute coronary syndrome, for instance, combining the two drugs may increase bleeding risk.
However, many doctors still recommend the combination for patients with minimal bleeding risk. One study found that over one-third of patients treated with warfarin and aspirin had an increased risk of bleeding. Another study found that patients who were on warfarin and aspirin together had a 50% higher risk of major bleeds.